At Modern Medicine, we help women uncover the root causes behind frustrating symptoms like painful periods, mood swings, infertility, and hormone imbalances. One of the most important—but often overlooked—factors? A common gene mutation called MTHFR.
Let’s break it down simply.
🧬 What Is MTHFR?
MTHFR is a gene that helps your body process folate (a B vitamin). If you have a mutation in this gene, your body may not produce enough methyl groups—the little chemical “helpers” needed to detox hormones like estrogen, support mood and energy, and even prepare your body for pregnancy.
💡 Why This Matters for Your Hormones
Your body makes and breaks down estrogen constantly. This balance is critical for a healthy cycle. Estrogen needs to peak in the first half of your cycle and drop afterward to make room for progesterone (your calming, cycle-balancing hormone).
If estrogen doesn’t get cleared properly, it can build up—leading to a condition called estrogen dominance. This can cause:
- – Heavy, painful periods
- – Breast tenderness
- – Mood swings
- – Infertility
- – Endometriosis
If you have an MTHFR mutation, your body may not be able to “turn off” or clear estrogen properly because it’s not making enough methyl groups. This can leave active estrogen hanging around in your system too long, creating chaos in your cycle.
🔁 The Estrogen Detox Bottleneck
To break down estrogen safely, your body methylates it—basically, it attaches a methyl group to neutralize it. MTHFR mutations slow that down, and suddenly you’re left with too much estrogen (and its irritating byproducts) in your system.
This matters not just for your hormones—but for your whole body:
- – Your gut health (which detoxifies hormones)
- – Your immune function (methylation supports it)
- – Your mood and brain chemistry (because methylation helps make neurotransmitters like dopamine, seretonin, etc. )
👩⚕️ How We Can Help at Modern Medicine
We test for MTHFR mutations, neurotransmitter levels, and hormones—because they’re all connected. If you’ve struggled to find answers for:
- – Infertility
- – PCOS
- – Irregular cycles
- – PMS/PMDD
- – Depression or anxiety
…you might benefit from this deeper look.
We use methylated B vitamins, nutritional support, gut healing, and hormone-balancing strategies to support your whole system—because band-aids don’t cut it here.
✅ Takeaways:
- If your estrogen is off and your periods or moods are a mess, it might be more than hormones—it could be your MTHFR gene.
- Estrogen needs to be detoxed, and your body can’t do that well without methylation.
- MTHFR can affect your cycle, mood, immunity, and fertility—but we can support it naturally.
If you want to stop guessing and start healing, schedule your MTHFR and hormone testing with our team today. You’re not broken—your body just needs the right support.
We can’t wait to support you!
Jade Green TNC, CHHC
